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florfenicol oral solution - high absorptivity, broad-spectrum antibacterial medicine, water soluble

Published:2012-7-16 15:34:23  Hits:1412

 
 
Florfenicol oral solution
1.This products circulates from liver to intestines which make it more easy for absorption at the intestines Its bioavailability is 8-10 times of chloramphenicol and Thiamphenicol.
 2. New type of chloramphenicol antibacterial drug, hardly cause drug resistance (since  Gene F on Alpha- methyl can't be destroyed by  acetyltransferase). And no cross resistance with other drugs.
3.Broad-spectrum antibacterial drug, effective both on Gram + and Gram - bacterias.
4.Long half-life period,(60 hours after using drug, average concertration reaches 0.39μ/ml)
5.In the form of oral solution, greatly increased the effect.
Experiment (1) florfenicol     (2) Thiamphenicol   (3) GANJIN
Group
NO. of chicken
Death
Severe cases
Mild case
No symptom
High dose
(1)
30
0
0
0
30
(2)
30
0
0
1
29
(3)
30
0
0
0
30
Middle dose
(1)
30
0
0
1
29
(2)
30
0
0
3
27
(3)
30
0
0
0
30
Low dose
(1)
30
0
0
2
28
(2)
30
1
0
5
22
(3)
30
0
0
0
30
Positive control group
30
1
11
7
11
Negative control group
30
0
0
0
30
Low dose of florfenicol has a better effect than Thiamphenicol.
Low and middle dose of florfenicol has a effective rate of 100% to E.coli.
Cure rate reaches 90%. 
Low dose and middle dose of Ganjin is 100% effective to E.coli and cure rate reaches 99.6%,.
 
Indication:

Enteritis, perihepatitis, pericarditis, especially effective on enterotoxemia and mix-infection of e coli and mycoplasma
 
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