Big Discount Sheep Ivermectin Solution - Nicolsamide tablet – Depond
Big Discount Sheep Ivermectin Solution - Nicolsamide tablet – Depond Detail:
Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.
Composition:
Each bolus cotnains 1250 mg niclosamide
Indication:
For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.
Dosage and Usage:
Orally each 1kg body weight.
Cattle: 40-60mg
Sheep: 60-70mg
Withdrawal period:
Sheep: 28 days.
Cattle:28 days.
Package size: 5 tablet per blister, 10 blister per box
Product detail pictures:
Related Product Guide:
Our target is to consolidate and improve the quality and service of existing products, meanwhile constantly develop new products to meet different customers' demands for Big Discount Sheep Ivermectin Solution - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Dominica, Istanbul, Latvia, With the development of the society and economy, our company will continue the "loyalty, dedication, efficiency, innovation" spirit of enterprise, and we will always adhere to the management idea of "would rather lose gold, do not lose customers heart". We will serve the domestic and foreign businessmen with sincere dedication, and let us create bright future together with you!
By King from Angola - 2017.10.13 10:47
The company's products can meet our diverse needs, and the price is cheap, the most important is that the quality is also very nice.
By Beatrice from Lebanon - 2017.09.26 12:12