product

China wholesale Fenbendazole Granule - Nicolsamide tablet – Depond

Short Description:


Product Detail

Related Video

Feedback (2)

Just about every member from our large efficiency income crew values customers' wants and enterprise communication for Cattle Fenbendazole Powder , 100ml Metamizole Injectable Solution , Amoxicillin Dosage , Our clients mainly distributed in the North America, Africa and Eastern Europe. we can supply high quality products with the very competitive price.
China wholesale Fenbendazole Granule - Nicolsamide tablet – Depond Detail:

Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.

Composition:

Each bolus cotnains 1250 mg niclosamide

Indication:

For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.

Dosage and Usage:

Orally each 1kg body weight.

Cattle: 40-60mg

Sheep: 60-70mg

Withdrawal period:

Sheep: 28 days.

Cattle:28 days.

Package size: 5 tablet per blister, 10 blister per box


Product detail pictures:

China wholesale Fenbendazole Granule - Nicolsamide tablet – Depond detail pictures


Related Product Guide:

We're committed to providing easy,time-saving and money-saving one-stop purchasing service of consumer for China wholesale Fenbendazole Granule - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Bulgaria, Barcelona, Salt Lake City, With good quality, reasonable price and sincere service, we enjoy a good reputation. Products are exported to South America, Australia, Southeast Asia and so on. Warmly welcome customers at home and abroad to cooperate with us for the brilliant future.
  • The company can keep up with the changes in this industry market, product updates fast and the price is cheap, this is our second cooperation, it's good.
    5 Stars By Victor from Saudi Arabia - 2018.12.22 12:52
    Although we are a small company, we are also respected. Reliable quality, sincere service and good credit, we are honored to be able to work with you!
    5 Stars By Bruno Cabrera from European - 2017.01.28 18:53
    Write your message here and send it to us