product

Chinese wholesale 22.2% Fenbendazole Granule - Nicolsamide tablet – Depond

Short Description:


Product Detail

Related Video

Feedback (2)

Our solutions are widely recognized and trusted by consumers and will meet up with constantly developing financial and social requires for 20ml Dexamethasone Injection , Oxytetracycline injection , Amoxicillin For Poultry , We warmly welcome all perspective inquiries from home and abroad to cooperate with us, and look forward to your correspondence.
Chinese wholesale 22.2% Fenbendazole Granule - Nicolsamide tablet – Depond Detail:

Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.

Composition:

Each bolus cotnains 1250 mg niclosamide

Indication:

For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.

Dosage and Usage:

Orally each 1kg body weight.

Cattle: 40-60mg

Sheep: 60-70mg

Withdrawal period:

Sheep: 28 days.

Cattle:28 days.

Package size: 5 tablet per blister, 10 blister per box


Product detail pictures:

Chinese wholesale 22.2% Fenbendazole Granule - Nicolsamide tablet – Depond detail pictures


Related Product Guide:

Our mission will be to become an innovative supplier of high-tech digital and communication devices by furnishing benefit added structure, world-class manufacturing, and service capabilities for Chinese wholesale 22.2% Fenbendazole Granule - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Portugal, luzern, Sacramento, With well educated, innovative and energetic staff, we are responsible for all elements of research, design, manufacture, sale and distribution. By studying and developing new techniques, we are not only following but also leading fashion industry. We listen attentively to the feedback from our customers and provide instant replies. You will instantly feel our professional and attentive service.
  • We feel easy to cooperate with this company, the supplier is very responsible, thanks.There will be more in-depth cooperation.
    5 Stars By Kama from Spain - 2018.06.26 19:27
    This manufacturers not only respected our choice and requirements, but also gave us a lot of good suggestions, ultimately, we successfully completed the procurement tasks.
    5 Stars By Pag from Burundi - 2018.07.27 12:26
    Write your message here and send it to us