product

Factory Free sample Cattle Avermectin Bolus - Nicolsamide tablet – Depond

Short Description:


Product Detail

Related Video

Feedback (2)

With a positive and progressive attitude to customer's interest, our enterprise continually improves our products excellent to meet the wants of customers and further focuses on safety, reliability, environmental requirements, and innovation of Enrofloxacin 10 Liquid , Sheep Vitamin B12 Solution , Analgine Injection , Welcome any of your inquiries and concerns for our products, we look forward to establishing a long-term business relationship with you in the near future. contact us today.
Factory Free sample Cattle Avermectin Bolus - Nicolsamide tablet – Depond Detail:

Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.

Composition:

Each bolus cotnains 1250 mg niclosamide

Indication:

For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.

Dosage and Usage:

Orally each 1kg body weight.

Cattle: 40-60mg

Sheep: 60-70mg

Withdrawal period:

Sheep: 28 days.

Cattle:28 days.

Package size: 5 tablet per blister, 10 blister per box


Product detail pictures:

Factory Free sample Cattle Avermectin Bolus - Nicolsamide tablet – Depond detail pictures


Related Product Guide:

We strive for excellence, services the customers", hopes to be the top cooperation team and dominator business for personnel, suppliers and prospects, realizes benefit share and continual promotion for Factory Free sample Cattle Avermectin Bolus - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Philippines, kazakhstan, Kenya, With the development and enlargement of mass clients abroad, now we have set up cooperative relationships with many major brands. We have our own factory and also have many reliable and well-cooperated factories in the field. Adhering to the "quality first, customer first, We are provideing high-quality, low-cost products and first-class service to customers. We sincerely hope to establish business relationship with customers from all over the world on the basis of quality, mutually benefit. We welcome OEM projects and designs.
  • Company director has very rich management experience and strict attitude, sales staff are warm and cheerful, technical staff are professional and responsible,so we have no worry about product,a nice manufacturer.
    5 Stars By Pandora from Yemen - 2017.12.31 14:53
    In China, we have many partners, this company is the most satisfying to us, reliable quality and good credit, it is worth appreciation.
    5 Stars By Dawn from Uruguay - 2018.06.18 19:26
    Write your message here and send it to us