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Free sample for 3mg Avermectin Bolus - Nicolsamide tablet – Depond

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We persist with the principle of "quality 1st, assistance initially, continual improvement and innovation to meet the customers" for your management and "zero defect, zero complaints" as the standard objective. To great our service, we present the products and solutions while using the very good top quality at the reasonable cost for Analgin Injection , Amoxicillin Powder For Poultry , Florfenicol Injection Cattle , The main goal of our company is to live a satisfactory memory to all the customers, and establish a long term business relationship with buyers and users all over the world.
Free sample for 3mg Avermectin Bolus - Nicolsamide tablet – Depond Detail:

Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.

Composition:

Each bolus cotnains 1250 mg niclosamide

Indication:

For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.

Dosage and Usage:

Orally each 1kg body weight.

Cattle: 40-60mg

Sheep: 60-70mg

Withdrawal period:

Sheep: 28 days.

Cattle:28 days.

Package size: 5 tablet per blister, 10 blister per box


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Free sample for 3mg Avermectin Bolus - Nicolsamide tablet – Depond detail pictures


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We stick with the theory of "quality first, company first, steady improvement and innovation to satisfy the customers" for the management and "zero defect, zero complaints" as the quality objective. To perfect our provider, we deliver the items together with the fantastic good quality at the reasonable value for Free sample for 3mg Avermectin Bolus - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Slovenia, Sydney, Argentina, Our company regards "reasonable prices, high quality,efficient production time and good after-sales service" as our tenet. We hope to cooperate with more customers for mutual development and benefits in future. Welcome to contact us.
  • As a veteran of this industry, we can say that the company can be a leader in the industry, select them is right.
    5 Stars By Dolores from Nepal - 2018.09.21 11:01
    The product manager is a very hot and professional person, we have a pleasant conversation, and finally we reached a consensus agreement.
    5 Stars By Fanny from Muscat - 2018.12.30 10:21
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