High Quality Fenbendazole Powder - Nicolsamide tablet – Depond
High Quality Fenbendazole Powder - Nicolsamide tablet – Depond Detail:
Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.
Composition:
Each bolus cotnains 1250 mg niclosamide
Indication:
For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.
Dosage and Usage:
Orally each 1kg body weight.
Cattle: 40-60mg
Sheep: 60-70mg
Withdrawal period:
Sheep: 28 days.
Cattle:28 days.
Package size: 5 tablet per blister, 10 blister per box
Product detail pictures:
Related Product Guide:
Reliable quality and good credit standing are our principles, which will help us at a top-ranking position. Adhering to the tenet of "quality first, customer supreme" for High Quality Fenbendazole Powder - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Austria, Mexico, Leicester, We mainly sell in wholesale, with the most popular and easy ways of making payment, which are paying via Money Gram, Western Union, Bank Transfer and Paypal. For any further talk, just feel free to contact our salesmen, who are really good and knowledgeable about our prodcuts.
By Gloria from Germany - 2017.01.28 18:53
After the signing of the contract, we received satisfactory goods in a short term, this is a commendable manufacturer.
By Joyce from South Africa - 2018.09.16 11:31