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High reputation Sheep Albendazole Solution - Nicolsamide tablet – Depond

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High reputation Sheep Albendazole Solution - Nicolsamide tablet – Depond Detail:

Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.

Composition:

Each bolus cotnains 1250 mg niclosamide

Indication:

For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.

Dosage and Usage:

Orally each 1kg body weight.

Cattle: 40-60mg

Sheep: 60-70mg

Withdrawal period:

Sheep: 28 days.

Cattle:28 days.

Package size: 5 tablet per blister, 10 blister per box


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High reputation Sheep Albendazole Solution - Nicolsamide tablet – Depond detail pictures


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Our personnel are always in the spirit of "continuous improvement and excellence", and together with the top-quality good quality solutions, favorable selling price and superior after-sales providers, we try to acquire each customer's rely on for High reputation Sheep Albendazole Solution - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Mexico, Suriname, Nicaragua, The company has perfect management system and after-sales service system. We devote ourselves to building a pioneer in the filter industry. Our factory is willing to cooperate with different customers domestic and overseas to gain better and better future.
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    5 Stars By Mona from Swaziland - 2017.10.27 12:12
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    5 Stars By Dolores from Buenos Aires - 2017.01.28 19:59
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