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Leading Manufacturer for 50ml Ivermectin Injectable Solution - Nicolsamide tablet – Depond

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Our enterprise since its inception, often regards solution excellent as enterprise life, continually strengthen output technology, enhance product high quality and continually strengthen organization total high-quality administration, in strict accordance using the national standard ISO 9001:2000 for Vitamin E Solution , Enrofloxacin Use In Cattle , Animal Vitamin B Injection , Customers first! Whatever you require, we should do our utmost to help you. We warmly welcome customers from all over the world to cooperate with us for mutual development.
Leading Manufacturer for 50ml Ivermectin Injectable Solution - Nicolsamide tablet – Depond Detail:

Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.

Composition:

Each bolus cotnains 1250 mg niclosamide

Indication:

For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.

Dosage and Usage:

Orally each 1kg body weight.

Cattle: 40-60mg

Sheep: 60-70mg

Withdrawal period:

Sheep: 28 days.

Cattle:28 days.

Package size: 5 tablet per blister, 10 blister per box


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Like a result of ours specialty and repair consciousness, our enterprise has won a superb popularity amid buyers everywhere in the environment for Leading Manufacturer for 50ml Ivermectin Injectable Solution - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Sydney, Seattle, US, Furthermore, all of our items are manufactured with advanced equipment and strict QC procedures in order to ensure high quality. If you are interested in any of our goods, please don't hesitate to contact us. We will do our best to meet your needs.
  • This is a reputable company, they have a high level of business management, good quality product and service, every cooperation is assured and delighted!
    5 Stars By Yannick Vergoz from Germany - 2017.12.02 14:11
    The goods we received and the sample sales staff display to us have the same quality, it is really a creditable manufacturer.
    5 Stars By Eunice from Latvia - 2017.01.11 17:15
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