product

Manufacturing Companies for Goat Avermectin Bolus - Nicolsamide tablet – Depond

Short Description:


Product Detail

Related Video

Feedback (2)

Our crew through skilled training. Skilled skilled knowledge, strong sense of company, to meet the company wants of customers for Vit B , Analgine , Tylosin Injection For Cattle , We warmly welcome merchants from your home and overseas to contact us and set up business enterprise partnership with us, and we'll do our greatest to serve you.
Manufacturing Companies for Goat Avermectin Bolus - Nicolsamide tablet – Depond Detail:

Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.

Composition:

Each bolus cotnains 1250 mg niclosamide

Indication:

For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.

Dosage and Usage:

Orally each 1kg body weight.

Cattle: 40-60mg

Sheep: 60-70mg

Withdrawal period:

Sheep: 28 days.

Cattle:28 days.

Package size: 5 tablet per blister, 10 blister per box


Product detail pictures:

Manufacturing Companies for Goat Avermectin Bolus - Nicolsamide tablet – Depond detail pictures


Related Product Guide:

Our commission is to serve our buyers and purchasers with most effective good quality and aggressive portable digital goods for Manufacturing Companies for Goat Avermectin Bolus - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Greece, Indonesia, Cyprus, To achieve reciprocal advantages, our company is widely boosting our tactics of globalization in terms of communication with overseas customers, fast delivery, the best quality and long-term cooperation. Our company upholds the spirit of "innovation, harmony, team work and sharing, trails, pragmatic progress". Give us a chance and we will prove our capability. With your kind help, we believe that we can create a bright future with you together.
  • The company has rich resources, advanced machinery, experienced workers and excellent services, hope you keep improving and perfecting your products and service, wish you better!
    5 Stars By Abigail from Sri Lanka - 2017.08.15 12:36
    It can be said that this is a best producer we encountered in China in this industry, we feel lucky to work with so excellent manufacturer.
    5 Stars By Dora from Sri Lanka - 2018.09.21 11:44
    Write your message here and send it to us