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Manufacturing Companies for Goat Avermectin Bolus - Nicolsamide tablet – Depond

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We offer great strength in quality and development,merchandising,sales and marketing and operation for Tylosin Soluble Powder , Enrofloxacin Injection For Swine , Enrofloxacin Injection Ip 10 W/V , Now we have experienced manufacturing facilities with extra than 100 employees. So we could guarantee short lead time and high quality assurance.
Manufacturing Companies for Goat Avermectin Bolus - Nicolsamide tablet – Depond Detail:

Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.

Composition:

Each bolus cotnains 1250 mg niclosamide

Indication:

For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.

Dosage and Usage:

Orally each 1kg body weight.

Cattle: 40-60mg

Sheep: 60-70mg

Withdrawal period:

Sheep: 28 days.

Cattle:28 days.

Package size: 5 tablet per blister, 10 blister per box


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Manufacturing Companies for Goat Avermectin Bolus - Nicolsamide tablet – Depond detail pictures


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abide by the contract", conforms on the market requirement, joins from the market competition by its good quality likewise as provides more comprehensive and superb support for customers to let them become large winner. The pursue of the company, is definitely the clients' pleasure for Manufacturing Companies for Goat Avermectin Bolus - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Greece, France, Ukraine, We follow up the career and aspiration of our elder generation, and we are eager to open up a new prospect in this field, We insist on "Integrity, Profession, Win-win Cooperation", because we have a strong backup, that are excellent partners with advanced manufacturing lines, abundant technical strength, standard inspection system and good production capacity.
  • The goods we received and the sample sales staff display to us have the same quality, it is really a creditable manufacturer.
    5 Stars By Ada from Poland - 2017.06.19 13:51
    In our cooperated wholesalers, this company has the best quality and reasonable price, they are our first choice.
    5 Stars By Yannick Vergoz from Ecuador - 2018.07.27 12:26
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