New Fashion Design for Ivermectin Solution - Nicolsamide tablet – Depond
New Fashion Design for Ivermectin Solution - Nicolsamide tablet – Depond Detail:
Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.
Composition:
Each bolus cotnains 1250 mg niclosamide
Indication:
For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.
Dosage and Usage:
Orally each 1kg body weight.
Cattle: 40-60mg
Sheep: 60-70mg
Withdrawal period:
Sheep: 28 days.
Cattle:28 days.
Package size: 5 tablet per blister, 10 blister per box
Product detail pictures:
Related Product Guide:
We keep on with the basic principle of "quality to start with, support very first, continuous improvement and innovation to meet the customers" for your management and "zero defect, zero complaints" as the quality objective. To great our service, we offer the items with all the superior top quality at the reasonable selling price for New Fashion Design for Ivermectin Solution - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Iceland, Bangladesh, India, Our production have been exported to more than 30 countries and regions as first hand source with lowest price. We sincerely welcome customers from both at home and abroad to come to negotiate business with us.
By Claire from Angola - 2018.07.26 16:51
Speaking of this cooperation with the Chinese manufacturer, I just want to say"well dodne", we are very satisfied.
By Josephine from British - 2017.08.15 12:36