product

OEM manufacturer Cattle Avermectin Tablet - Nicolsamide tablet – Depond

Short Description:


Product Detail

Related Video

Feedback (2)

Using a complete scientific top quality management program, great high-quality and fantastic religion, we win great track record and occupied this area for Tilmicosin Bovine , 3mg Avermectin Bolus , Ivermectin Oral Solution , We are confident that there will be a promising future and we hope we can have long term cooperation with customers from all over the world.
OEM manufacturer Cattle Avermectin Tablet - Nicolsamide tablet – Depond Detail:

Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.

Composition:

Each bolus cotnains 1250 mg niclosamide

Indication:

For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.

Dosage and Usage:

Orally each 1kg body weight.

Cattle: 40-60mg

Sheep: 60-70mg

Withdrawal period:

Sheep: 28 days.

Cattle:28 days.

Package size: 5 tablet per blister, 10 blister per box


Product detail pictures:

OEM manufacturer Cattle Avermectin Tablet - Nicolsamide tablet – Depond detail pictures


Related Product Guide:

We've been committed to offering easy,time-saving and money-saving one-stop purchasing service of consumer for OEM manufacturer Cattle Avermectin Tablet - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Kenya, Japan, Pakistan, With the spirit of "credit first, development through innovation, sincere cooperation and joint growth", our company is striving to create a brilliant future with you, so as to become a most valuable platform for exporting our goods in China!
  • The customer service reprersentative explained very detailed, service attitude is very good, reply is very timely and comprehensive, a happy communication! We hope to have a opportunity to cooperate.
    5 Stars By Jean from Czech Republic - 2018.10.31 10:02
    The company can keep up with the changes in this industry market, product updates fast and the price is cheap, this is our second cooperation, it's good.
    5 Stars By Dorothy from Tanzania - 2017.04.08 14:55
    Write your message here and send it to us