Personlized Products Goat Ivermectin Injectable Solution - Nicolsamide tablet – Depond
Personlized Products Goat Ivermectin Injectable Solution - Nicolsamide tablet – Depond Detail:
Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.
Composition:
Each bolus cotnains 1250 mg niclosamide
Indication:
For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.
Dosage and Usage:
Orally each 1kg body weight.
Cattle: 40-60mg
Sheep: 60-70mg
Withdrawal period:
Sheep: 28 days.
Cattle:28 days.
Package size: 5 tablet per blister, 10 blister per box
Product detail pictures:
Related Product Guide:
Reliable quality and good credit standing are our principles, which will help us at a top-ranking position. Adhering to the tenet of "quality first, customer supreme" for Personlized Products Goat Ivermectin Injectable Solution - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Oman, Riyadh, Lyon, Customer satisfaction is our goal. We are looking forward to cooperating with you and providing our best services to suit your needs. We warmly welcome you to contact us and make sure you feel free to contact us. Browse our online showroom to see what we can do for you. And then E-mail us your specs or inquiries today.
By Janet from Afghanistan - 2018.07.12 12:19
It's really lucky to find such a professional and responsible manufacturer, the product quality is good and delivery is timely, very nice.
By Rosemary from Estonia - 2017.09.30 16:36