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Popular Design for Animal Ivermectin Injectable Solution - Nicolsamide tablet – Depond

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With reliable quality process, good reputation and perfect customer service, the series of products produced by our company are exported to many countries and regions for Erythromycin Veterinary , Goat Vitamin Injection , Tylosin Tartrate , Welcome any of your inquiries and concerns for our products, we look forward to establishing a long-term business relationship with you in the near future. contact us today.
Popular Design for Animal Ivermectin Injectable Solution - Nicolsamide tablet – Depond Detail:

Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.

Composition:

Each bolus cotnains 1250 mg niclosamide

Indication:

For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.

Dosage and Usage:

Orally each 1kg body weight.

Cattle: 40-60mg

Sheep: 60-70mg

Withdrawal period:

Sheep: 28 days.

Cattle:28 days.

Package size: 5 tablet per blister, 10 blister per box


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Now we have highly developed devices. Our items are exported towards the USA, the UK and so on, enjoying a great popularity among the customers for Popular Design for Animal Ivermectin Injectable Solution - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Orlando, Ecuador, Croatia, We've got a dedicated and aggressive sales team, and many branches, catering to our customers. We are looking for long-term business partnerships, and ensure our suppliers that they will absolutely benefit in both short and long run.
  • In China, we have many partners, this company is the most satisfying to us, reliable quality and good credit, it is worth appreciation.
    5 Stars By Rosalind from Cyprus - 2018.10.01 14:14
    The goods we received and the sample sales staff display to us have the same quality, it is really a creditable manufacturer.
    5 Stars By Eleanore from Cancun - 2017.06.25 12:48
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