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professional factory for Sheep Ivermectin Bolus - Nicolsamide tablet – Depond

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Innovation, quality and reliability are the core values of our company. These principles today more than ever form the basis of our success as an internationally active mid-size company for Oxytetracycline injection , Tylosin Injection For Cattle , Enrofloxacin Injectable , Your inquiry will be highly welcomed and a win-win prosperous development are what we are expecting.
professional factory for Sheep Ivermectin Bolus - Nicolsamide tablet – Depond Detail:

Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.

Composition:

Each bolus cotnains 1250 mg niclosamide

Indication:

For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.

Dosage and Usage:

Orally each 1kg body weight.

Cattle: 40-60mg

Sheep: 60-70mg

Withdrawal period:

Sheep: 28 days.

Cattle:28 days.

Package size: 5 tablet per blister, 10 blister per box


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It is our responsibility to meet your needs and efficiently serve you. Your satisfaction is our best reward. We are looking forward to your visit for joint growth for professional factory for Sheep Ivermectin Bolus - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Casablanca, Belize, Lahore, We also provide OEM service that caters to your specific needs and requirements. With a strong team of experienced engineers in hose design and development, we value every opportunity to provide best products for our customers.
  • We are long-term partners, there is no disappointment every time, we hope to maintain this friendship later!
    5 Stars By Marina from Mauritania - 2018.11.28 16:25
    The factory has advanced equipment, experienced staffs and good management level, so product quality had assurance, this cooperation is very relaxed and happy!
    5 Stars By Jessie from Melbourne - 2017.12.19 11:10
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