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Top Suppliers Goat Avermectin Tablet - Nicolsamide tablet – Depond

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Our corporation insists all along the quality policy of "product top quality is base of organization survival; purchaser pleasure will be the staring point and ending of an company; persistent improvement is eternal pursuit of staff" plus the consistent purpose of "reputation very first, purchaser first" for 50ml Metamizole Sodium Injectable Solution , Cattle Vitamin Injection , Vit B12 Injection , We will supply best quality, the most market competitive price, for every new and old customers with the most perfect green services.
Top Suppliers Goat Avermectin Tablet - Nicolsamide tablet – Depond Detail:

Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.

Composition:

Each bolus cotnains 1250 mg niclosamide

Indication:

For ruminants infected paramphistomes, cestodiasis, such as cattle and sheep’s moniezia, avitellina centripunctata, etc.

Dosage and Usage:

Orally each 1kg body weight.

Cattle: 40-60mg

Sheep: 60-70mg

Withdrawal period:

Sheep: 28 days.

Cattle:28 days.

Package size: 5 tablet per blister, 10 blister per box


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Our development depends on the advanced equipment ,excellent talents and continuously strengthened technology forces for Top Suppliers Goat Avermectin Tablet - Nicolsamide tablet – Depond , The product will supply to all over the world, such as: Kuala Lumpur, Barcelona, UAE, We warmly welcome domestic and overseas customers to visit our company and have business talk. Our company always insists on the principle of "good quality, reasonable price, the first-class service". We are willing to build long-term, friendly and mutually beneficial cooperation with you.
  • Good quality and fast delivery, it's very nice. Some products have a little bit problem, but the supplier replaced timely, overall, we are satisfied.
    5 Stars By Iris from Uganda - 2017.12.19 11:10
    A nice supplier in this industry, after a detail and careful discussion, we reached a consensus agreement. Hope that we cooperate smoothly.
    5 Stars By Sabina from Chicago - 2018.06.18 19:26
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